Name Mr. Rahul Shubhra Mandal
Educational Qualification M.Sc.(Tech) Bioinformatics
Designation Scientist I
Division Biomedical Informatics Centre
E-mail shubhra.rahul@gmail.com
Research Interest Structural Bioinformatics & Drug Designing, NGS data analysis, Artificial intelligence
Date of joining ICMR 1st March, 2012  
 

Educational qualifications

  • M.Sc. (Tech) in Bioinformatics, West Bengal University of Technology, Kolkata, India, 2009.

  • B-Level in Bioinformatics, DOEACC Society, Kolkata, India, 2007.

  • B.Sc. in Zoology (H), City College, Kolkata, Calcutta University, Kolkata, India, 2005.

Awards and achievements

  • BioAsia Innovation Award 2015, February 2015, HICC, Hyderabad.

  • Received International Travel Support from Department of Science and Technology, Government of India, (ITS/4315/2017-18) for attending From Single- to Multiomics: Applications and Challenges in Data Integration held during 12 th - 14 th Nov 2017 at EMBL Heidelberg, Germany.

  • Received International Travel Support from Department of Science and Technology, Government of India (SB/ITS/03296/2014-15) for attending the 5th ACM Conf. on Bioinformatics, Computational Biology and Health Informatics, September 2014, California, USA.

  • Awarded with Second prize for presenting a poster at the conference titled "Recent Advances in Computational Drug Designing" at IISC, Bangalore 16-17 Sept. 2013.

Publications   Google Scholar   ResearchGate

    2017
  1. Mukherjee SK, Rahul S. Mandal, Das S, Mukherjee M. 2017 Effect of non β-lactams on stable variants of inhibitor resistant TEM β-lactamase in uropathogenic E. coli : Implication for alternative therapy. J Appl Microbiol. PubMed Link

  2. Jana S, Patel D, Patel S, Upadhyay K, Thadani J, Rahul S. Mandal, Das S, Devkar R. 2017. Anthocyanin rich extract of Brassica oleracea L. alleviates experimentally induced myocardial infarction. PLoS One. PubMed Link

  3. Rahul S. Mandal, Samiran Panda, Santasabuj Das. 2017. In silico prediction of drug resistance due to S247R mutation of Influenza H1N1 neuraminidase protein. J Biomol Struct Dyn. PubMed Link

  4. 2016
  5. Ramachandran Muthiyan, Balwin Nambikkairaj, Nilkamal Mahanta1, Titus Immanuel, Rahul S. Mandal, Kubendiran Kumaran, Arun Kumar De. 2016. Antiproliferative and Proapoptotic Activities of Marine Sponge Hyrtios erectus Extract on Breast Carcinoma Cell Line (MCF-7). Pharmacognosy Magazine. PubMed Link

  6. Rahul S. Mandal, Atri Ta, Ritam Sinha, Nagaraja Theeya, Anirban Ghosh, Mohsina Tasneem, Anirban Bhunia, Hemanta Koley & Santasabuj Das. 2016. Ribavirin suppresses bacterial virulence by targeting LysR-type transcriptional regulators. Scientific Reports. PubMed Link

  7. Preetida J. Bhetariya, Madhvi Prajapati, Asani Bhaduri, Rahul S. Mandal, Anupam Varma, Taruna Madan, Yogendra Singh and P. Usha Sarma. 2016. Phylogenetic and Structural Analysis of Polyketide Synthases in Aspergilli. Evol Bioinform Online. PubMed Link

  8. 2015
  9. Gaurab Sircar, Bodhisattwa Saha, Rahul S. Mandal, Naren Pandey, Sudipto Saha, Swati Gupta Bhattacharya. 2015. Purification, Cloning and Immuno-Biochemical Characterization of a Fungal Aspartic Protease Allergen Rhi o 1 from the Airborne Mold Rhizopus oryzae. PLoS One. PubMed Link

  10. Nagaraja Theeya, Atri Ta, Sayan Das, Rahul S. Mandal, Oishee Chakrabarti, Saikat Chakrabarti, Amar N. Ghosh and Santasabuj Das*. An Inducible and Secreted Eukaryotic-like Serine/1 Threonine Kinase of Salmonella Typhi Promotes Intracellular Survival and Pathogenesis. Infection and Immunity. 2015; doi: 10.1128/IAI.02521-14. PubMed Link

  11. Rahul S. Mandal, Sudipto Saha*, Santasabuj Das*. 2015. Metagenomic surveys of gut microbiota. Genomics, Proteomics & Bioinformatics. PubMed Link


  12. 2014
  13. Rimi Chowdhury, Rahul S. Mandal, Atri Ta, Santasabuj Das*. An AIL family protein promotes Type Three Secretion System-1 independent invasion and pathogenesis of Salmonella enterica serovar Typhi. Cellular microbiology, doi: 10.1111/cmi.12379. PubMed Link

  14. Arora G, Tiwari P, Rahul S. Mandal, Gupta A, Sharma D, Saha S, Singh R*. High Throughput Screen Identifies Small Molecule Inhibitors Specific for Mycobacterium tuberculosis Phosphoserine Phosphatase. J. Biol. Chem. 2014 Jul 18; doi: 10.1074/jbc.M114.597682. PubMed Link

  15. Amrita Bhattacherjee, Rahul S. Mandal, Santasabuj Das, Sudip Kundu* Sequence and 3D Structure based analysis of TNT degrading proteins in Arabidopsis thaliana. J Mol Model. 2014 Mar; 20(3):2174. doi: 10.1007/s00894-014-2174-z. PubMed Link

  16. Vikash Kumar Yadav, Rahul S. Mandal, Bhanwar Lal Puniya, Rahul Kumar, Sharmistha Dey, Sarman Singh, Savita Yadav*. Structural and binding studies of SAP-1 protein with heparin. Chemical Biology & Drug Design.2014; doi: 10.1111/cbdd.12420. PubMed Link

  17. Rahul S. Mandal and Santasabuj Das*. In silico approach towards identification of potential inhibitors of Helicobacter pylori dapE. J Biomol Struct Dyn. 2014. doi: 10.1080/07391102.2014.954272. PubMed Link



  18. 2013
  19. Vikash Kumar Yadav, Rahul S. Mandal, Bhanwar Lal Puniya, Sarman Singh, Savita Yadav*. Studies on the interaction of SAP-1 (an N-terminal truncated form of cystatin S) with its binding partners by CD-spectroscopic and molecular docking methods. J Biomol Struct Dyn. 2013; Nov 21. PubMed Link

  20. Sriyans Jain, Rahul S. Mandal, Swadha Anand, Souvik Maiti, Srinivasan Ramachandran*. Probing the amino acids critical for protein oligomerisation and protein-nucleotide interaction in Mycobacterium tuberculosis PII protein through integration of computational and experimental approaches. Biochim Biophys Acta. 2013 Dec; 1834(12):2736-49. PubMed Link

  21. Jayadev Joshi, Tapan K. Barik, Nitisha Shrivastava, Manali Dimri, Subhajit Ghosh, Rahul S. Mandal, Srinivasan Ramachandran and Indracanti P. Kumar*. Cycloxygenase-2 (COX-2) as a potential target for screening of small molecules as radiation countermeasure agents: An in silico study. Current Computer - Aided Drug Design, Volume 9, Number 1, March 2013; pp. 35-45(11). PubMed Link



  22. 2012
  23. Shachi Gahoi#, Rahul S. Mandal#, Nikita Ivanisenko, Ashish K. Singh, Muthukurrusi V. Raghunandanan, Swarna Kanchan, Chhabinath Mandal, Vladimir A. Ivanisenko, [Open Source Drug Discovery Consortium], Srinivasan Ramachandran*. A serial enrichment approach of Computational Screening for new inhibitors of M.tuberculosis mycolyltransferases antigen 85 group of proteins as potential drug targets. J Biomol Struct Dyn. 2012; 31(1):30-43.
    #Equal contribution.
    PubMed Link



  24. 2011
  25. Sagarika Biswas*, Sandeep K. Kushwaha, Rahul S. Mandal, Saugata Roy and H. R. Das. Structural Model Based Designing of Inhibitors for Glial Fibrillary Acidic Protein. Annals of Biological Research, 2011; 2(1):40-50. Link


  26. Book Chapter

  27. Rahul S. Mandal, Santasabuj Das. (2017). In Silico Approaches Toward Combating Antibiotic Resistance. Springer Nature. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer, 577-593. Bookchapter Link

  28. Srinivasan Ramachandran, Rupanjali Chaudhuri, Srikant Prasad Verma, Ab Rauf Shah, Chaitali Paul, Shreya Chakraborty, Bhanwar Lal Puniya and Rahul S. Mandal (2011). Biological Data Modelling and Scripting in R. InTech. Systems and Computational Biology - Bioinformatics and Computational Modeling, Ning-Sun Yang (Ed.), ISBN: 978-953-307-875-5,   Bookchapter Link